April 06, 2022
The printing process does not harm the cells
"Our results indicate that the bio-ink combination we used, combined with the
micro-channels, provides the right environment to keep the cells alive and to
support cell and tissue growth," said Atala. The scientists said they printed
ear, bone and muscle structures using a sophisticated, custom-designed 3D
printer. In addition, a strong, temporary outer structure is formed.For years,
printing functional organs and body parts, like ear, jaw and muscle, has been
nothing but science fiction, but now, a study claims that it is possible in real
life too. The study appears in Nature Biotechnology. When implanted in animals,
the structures matured into functional tissue and developed a system of blood
vessels. The Wake Forest Baptist scientists addressed this in two ways.The
scientists said they printed ear, bone and muscle structures.Using a
sophisticated, custom-designed 3D printer, regenerative medicine scientists at
Wake Forest Baptist Medical Center have proved that it is feasible to print
living tissue structures to replace injured or diseased tissue in
patients.Senior author Anthony Atala said that this novel tissue and organ
printer is an important advance in our quest to make replacement tissue for
patients, adding that it can fabricate stable, human-scale tissue of any shape.
The printing process does not harm the cells. The system deposits both
bio-degradable, plastic-like materials to form the tissue "shape" and
water-based gels that contain the cells. These channels allow nutrients and
oxygen from the body to diffuse into the structures and keep them live while
they develop a plastic plate
Manufacturers system of blood vessels.A major challenge of tissue
engineering is ensuring that implanted structures live long enough to integrate
with the body. With further development, this technology could potentially be
used to print living tissue and organ structures for surgical implantation.The
scientists said they printed ear, bone and muscle structures using a
sophisticated, custom-designed 3D printer. Most importantly, these early results
indicate that the structures have the right size, strength and function for use
in humans. 3D technology could potentially be used to print living tissue and
organ structures for surgical implantation.The ITOP system was also able to use
data from CT and MRI scans, allowing the researchers to 'tailor' tissue for
patients.The Integrated Tissue and Organ Printing System (ITOP), developed over
a 10-year period by scientists at the Institute for Regenerative Medicine,
overcomes these challenges. They optimized the water-based "ink" that holds the
cells so that it promotes cell health and growth and they printed a lattice of
micro-channels throughout the structures
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